| Athletic | costs 10 | +4 Fitness; faster running, slower endurance loss | Not with Fit, Unfit, Out of Shape, Smoker |
| Strong | costs 10 | +4 Strength; more knockback and carry weight | Not with Stout, Weak, Puny |
| Bushcrafter | costs 8 | +1 Foraging, Knapping, Maintenance, Carving; herbs and stone tools | Was Wilderness Knowledge (42.0) |
| Handy | costs 8 | +1 Carpentry, Carving, Maintenance, Masonry; faster, stronger builds | – |
| Hunter | costs 8 | +1 Aiming, Tracking, Sneaking, Short Blade, Butchering | – |
| Thick-skinned | costs 8 | Scratches and bites break the skin less often | Not with Thin-skinned |
| Blacksmith Knowledge | costs 6 | +2 Blacksmithing, +1 Maintenance; can use an anvil | New in B42 |
| Brawler | costs 6 | +1 Axe, +1 Long Blunt | – |
| Fast Healer | costs 6 | Faster recovery from injury and illness | Not with Slow Healer |
| Fast Learner | costs 6 | More XP from everything | Not with Slow Learner, Crafty |
| Fit | costs 6 | +2 Fitness | Not with Athletic, Unfit, Out of Shape |
| Former Scout | costs 6 | +1 First Aid, +1 Foraging, +1 Fishing; faster bow-drill fires | – |
| Keen Hearing | costs 6 | Larger perception radius | Not with Deaf, Hard of Hearing |
| Stout | costs 6 | +2 Strength | Not with Strong, Weak, Puny |
| Gymnast | costs 5 | +1 Lightfooted, +1 Nimble | – |
| Hiker | costs 5 | +1 Foraging, +1 Trapping | – |
| Target Shooter | costs 5 | +1 Aiming | New in 42.16 |
| Adrenaline Junkie | costs 4 | Moves faster when very panicked | Not with Brave, Cowardly, phobias, Desensitized |
| Angler | costs 4 | +1 Fishing | – |
| Baseball Player | costs 4 | +1 Long Blunt | – |
| Brave | costs 4 | Panics less | Not with Cowardly, phobias |
| Eagle Eyed | costs 4 | Longer view distance, better sights at range | Not with Short Sighted |
| Graceful | costs 4 | Less noise when moving | Not with Clumsy |
| Herbalist | costs 4 | +1 Foraging; finds medicinal herbs, makes poultices | – |
| Inconspicuous | costs 4 | Zombies spot you less | Not with Conspicuous |
| Organized | costs 4 | Bigger container capacity | Not with Disorganized |
| Resilient | costs 4 | Less disease, slower zombification | Not with Prone to Illness |
| Runner | costs 4 | +1 Running | – |
| Sewer | costs 4 | +1 Tailoring | – |
| Tinkerer | costs 4 | +1 Maintenance | New in 42.16 |
| Cat's Eyes | costs 3 | Better night vision | – |
| Crafty | costs 3 | More XP for crafting skills | New in B42. Not with Fast or Slow Learner |
| Keen Cook | costs 3 | +2 Cooking, +1 Butchering; cooking recipes | Was Cook in B41 |
| Vehicle Knowledge | costs 3 | +1 Mechanics; knows common vehicles | Was Amateur Mechanic |
| Wakeful | costs 3 | Needs less sleep | Not with Sleepyhead |
| Artisan | costs 2 | +1 Glassmaking, +1 Pottery | New in B42 |
| Dextrous | costs 2 | Faster item transfers and climbing | Not with All Thumbs |
| Fast Reader | costs 2 | Reads faster | Not with Slow Reader, Illiterate |
| First Aider | costs 2 | +1 First Aid | – |
| Gardener | costs 2 | +1 Agriculture; growing and pest recipes | – |
| Inventive | costs 2 | Lower skill needed to research recipes | New in B42 |
| Iron Gut | costs 2 | Less food poisoning | Not with Weak Stomach |
| Light Eater | costs 2 | Needs less food | Not with Hearty Appetite |
| Low Thirst | costs 2 | Needs less water | Not with High Thirst |
| Mason | costs 2 | +2 Masonry | New in B42 |
| Nutritionist | costs 2 | Sees nutrition values on all food | – |
| Outdoorsy | costs 2 | Less affected by harsh weather | Was Outdoorsman |
| Whittler | costs 2 | +2 Carving; wood and bone items | New in B42 |
| Speed Demon | costs 1 | Drives faster | Not with Sunday Driver |
| Deaf | gives 12 | Cannot hear | Not with Hard of Hearing, Keen Hearing |
| Illiterate | gives 10 | Cannot read books or signs | Not with Fast or Slow Reader |
| Puny | gives 10 | −5 Strength; very low carry weight | Was Weak in B41 |
| Unfit | gives 10 | −4 Fitness; very low endurance | Not with Athletic, Fit, Out of Shape |
| Thin-skinned | gives 8 | Scratches and bites break the skin more often | Not with Thick-skinned |
| Disorganized | gives 6 | Smaller container capacity | Not with Organized |
| Out of Shape | gives 6 | −2 Fitness | – |
| Restless Sleeper | gives 6 | Sleep restores less | – |
| Slow Learner | gives 6 | Less XP from everything | Not with Fast Learner, Crafty |
| Weak | gives 6 | −2 Strength | Was Feeble in B41 |
| Fear of Blood | gives 5 | Panics treating wounds; cannot treat others | Was Hemophobic |
| Reluctant Fighter | gives 5 | Less combat XP | Was Pacifist |
| Short of Breath | gives 5 | Loses endurance faster | Was Asthmatic |
| Agoraphobic | gives 4 | Panics outdoors | Not with Claustrophobic, Brave |
| Claustrophobic | gives 4 | Panics in small rooms | Not with Agoraphobic, Brave |
| Conspicuous | gives 4 | Zombies spot you more | Not with Inconspicuous |
| Hard of Hearing | gives 4 | Smaller hearing range | Not with Deaf, Keen Hearing |
| Hearty Appetite | gives 4 | Needs more food | Not with Light Eater |
| Prone to Illness | gives 4 | More disease, faster zombification | Not with Resilient |
| Sleepyhead | gives 4 | Needs more sleep | Not with Wakeful |
| Slow Healer | gives 3 | Slower recovery | Not with Fast Healer |
| Smoker | gives 3 | Unhappy without tobacco; smoking cuts stress | Not with Athletic |
| All Thumbs | gives 2 | Slow transfers; no crafting while walking | Not with Dextrous |
| Clumsy | gives 2 | Noisier movement | Not with Graceful |
| Cowardly | gives 2 | Panics easily | Not with Brave |
| Fast Metabolism | gives 2 | Loses weight; starts at Low Weight | New in B42 |
| High Thirst | gives 2 | Needs more water | Not with Low Thirst |
| Short Sighted | gives 2 | Shorter view, weaker sights | Not with Eagle Eyed |
| Slow Metabolism | gives 2 | Gains weight; starts at High Weight | New in B42 |
| Slow Reader | gives 2 | Reads slower | Not with Fast Reader, Illiterate |
| Weak Stomach | gives 2 | More food poisoning | Not with Iron Gut |
| Sunday Driver | gives 1 | Drives very slowly | Not with Speed Demon |
| Ax-pert | free | Faster axe swings and tree chopping | Lumberjack only |
| Burglar | free | Hotwire cars; breaks fewer window locks | Burglar only |
| Desensitized | free | Almost no panic; immune to Discomfort | Veteran only |
| Night Owl | free | Needs little sleep, alert while asleep | Nurse, Security Guard |
